Nanomicelles loaded with doxorubicin and curcumin for alleviating multidrug resistance in lung cancer
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منابع مشابه
Nanomicelles loaded with doxorubicin and curcumin for alleviating multidrug resistance in lung cancer
PURPOSE A new type of polymeric micelle (PM) was assembled using a polyethylene glycol (PEG)-linked (PEGylated) amphiphilic copolymer and d-tocopheryl PEG1000 succinate (TPGS1000). The micelles were used to deliver doxorubicin (DOX) and curcumin (CUR) for alleviating multidrug resistance (MDR) in lung cancer cells while enhancing the therapeutic efficacy of DOX. METHODS Micelles loaded with D...
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State Key Laboratory of Natural Medic Evaluation and Translational Research, D TCM, China Pharmaceutical University, [email protected]; [email protected] 86185158 College of Chemistry, Chemical Enginee Provincial Key Laboratory of Clean Product University, 250014, P. R. China † Electronic supplementary information ( gures. See DOI: 10.1039/c7ra01128h ‡ Both authors contributed equally to thi ...
متن کاملSurfactin-based nanoparticles loaded with doxorubicin to overcome multidrug resistance in cancers
Background Multidrug resistance (MDR) is one of the major obstacles to successful cancer chemotherapy. Developing efficient strategies to reverse MDR remains a major challenge. Surfactin (SUR), a cyclic lipopeptide biosurfactant, has been found to display anticancer activity. Methods In this paper, SUR was assembled by solvent-emulsion method to load the anticancer drug doxorubicin (DOX). The...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2016
ISSN: 1178-2013
DOI: 10.2147/ijn.s118568